Chondroitin Sulfate

The body uses chondroitin sulfate as a major building block of healthy joint tissue. The two primary components of cartilage are collagen and proteoglycans.

• Collagen – Consists of long strands of protein.
• Proteoglycans – Consists of a protein/hyaluronic acid backbone with branches of long chain repeating sugars called glycosaminoglycans (GAGs). The most predominant GAG is chondroitin sulfate (CS).

Proteoglycans, containing their substantial amount of CS, are intertwined with the collagen fibers. The CS portion is known as a “water magnet.” This water-holding quality gives structure to the cartilage and acts as a “shock absorber” during daily activity and movement.

As with all body tissues, cartilage components are constantly affected by normal wear and tear. In a healthy body, the tissue is constantly maintained and restored. It is possible to support this ongoing joint tissue maintenance by providing the body with supplemental levels of CS. Although the exact mechanism is not known, it is generally believed that CS and its metabolites are absorbed into the blood stream from the GI tract, transported to joints, and used by the body for the ongoing creation of proteoglycans. This can potentially enhance overall maintenance of healthy cartilage and, consequently, promote healthy and comfortable range of motion.*

Recent research has found that CS is most effective when taken in conjunction with glucosamine. And the maintenance activity of these two joint tissue building blocks can be further enhanced by the addition of hyaluronic acid and/or MSM. Wilke Resources provides high-quality sources for all four joint support ingredients. We can help you upgrade your existing product or create a new joint health formula that meets and exceeds your customers’ expectations.*

Chondropure™ - A Competitive Edge for Joint Health Formulas

Sioux Pharm’s Chondropure™ Chondroitin Sulfate is a natural extract of bovine cartilage that conforms to the USP monograph for chondroitin sulfate 90%. It is derived solely
from frozen bovine sources at USDA-inspected meat packaging and processing plants in the United States.

• The only self-affirmed GRAS chondroitin sulfate available; safe for food use.
• Product certified BSE-free by its suppliers.
• GMP plant uses only bovine cartilage from USDA-certified beef.
• Sioux Pharm maintains a Drug Master File with the FDA on the manufacture of Chondropure™.
• Conforms to the USP Monograph for chondroitin sulfate 90%.

The recommended daily dosage for Chondropure™ USP is 1,200 mg per day. For best results, it is normally combined with 1,500 mg of glucosamine HCl and 15 mg of hyaluronic acid (HA).

1USP Monograph assay specifications for chondroitin sulfate 90% are based on using USP standard reference samples, which are purer than Sigma Aldrich’s reference standards. The difference can be as much as 5 percentage points.

Why Ingredients from Wilke Resources?

Wilke Resources is a respected name in quality bulk nutritional supplements, offering raw ingredient products to the pharmaceutical, health-nutrition, and animal health markets. Wilke serves as both a sales and marketing agent for selected U.S. manufacturers and provides high-quality bulk dietary supplement ingredients through its China Direct sourcing program.

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