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14321 W. 96th Terrace, Lenexa, KS 66215
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Animathyl™ Spinach Extract: A natural approach toward pet weight management!

Weight management is a major health challenge that influences metabolic and cardiovascular health for humans worldwide. It’s beginning to affect more and more pets too, due to pet food quality and lifestyle choices of pet owners. A growing number of pet owners, often alerted to their own need for dietary improvements, are looking for natural approaches to helping their canine companions get healthy and fit as well. Natural products designed specifically for pets are in increasing demand.

Dogs and cats, like any mammals, can struggle with weight issues due to compromised satiety response. One important gastrointestinal satiety signal is cholecystokinin (CCK), released from the intestine by the entry of dietary fat and protein. It has been shown that dietary fat induces satiety as long as it is present in the intestines. It is possible to support this satiety signal through certain natural supplements. One such supplement is a derivative of spinach leaves, called thylakoids.*

How do thylakoids work?

The enzyme responsible for the main intestinal fat digestion is pancreatic lipase and its cofactor colipase. It has been proven that thylakoid membranes inhibit the activity of pancreatic lipase/colipase in vitro. Two mechanisms are suggested for this inhibition:

  • adsorption of the lipase/colipase to the thylakoid membranes, supported by binding experiments
  • OR adsorption of the thylakoid membranes on the lipid droplets, supported by electron microscopy pictures.

In both mechanisms of action, access of the lipase/colipase complex to the lipid substrate is hindered. Regardless of the exact MOA, there are two prominent results in the weight management equation:

  • The animal feels full sooner and for a longer duration.*
  • Actual digestion of fat is hindered, resulting in regulation of dietary fat absorption into the body.*


Animathyl™ Thylakoids for Superior, Proven Results

The thylakoid membrane proteins found in Animathyl™ Spinach Extract have been rigorously tested in both human and animal models. The ingredient has been successfully proven to support healthy satiety, promote healthy cholecystokinin (CCK) levels, and help maintain balanced serum triglycerides and insulin levels. Animathyl™ thylakoids have been found to be remarkably resistant towards the proteases pepsin, trypsin as well as towards whole gastric and pancreatic juice. That results in a product that remains intact during digestion to successfully deliver its effects in the intestines.* 

Animathyl™ Spinach Extract is produced by the Swedish research and development company, Greenleaf Medical. The Company is dedicated to developing natural ingredients with well-documented, beneficial health effects, and has crafted ingredients both for the animal and human markets. 

Greenleaf’s Animathyl™ powder ingredient is remarkably stable even at high heat, resulting in a two to three-year shelf life.  It provides a 57 percent minimum lipase activity regulation, though it can be as high as 65 percent.  Recommended dosage reference points are 500 mg for a 25-pound dog and 1,000 mg for a 50-pound dog.


Why Ingredients from Wilke Resources?

Wilke Resources is a respected name in quality bulk nutritional supplements, offering raw ingredient products to the pharmaceutical, health-nutrition, and animal health markets. Wilke serves as both a sales and marketing agent for selected U.S. manufacturers and provides high-quality bulk dietary supplement ingredients through its China Direct sourcing program.



*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

As a supplier of bulk dietary supplement ingredients, it is not our intent to suggest that our customers may
claim that our ingredients prevent, treat, or cure any infection or disease or remedy any other condition. Our ingredients may promote the whole health and wellness of specific body systems when taken as directed. Consumers should consult their physicians before adding any dietary supplement to their daily wellness program.